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Recent Amendments & Revogações (Repeals)

ANVISA regulations change frequently. This page summarises significant recent amendments and repeals relevant to medical device regulation.

The 2022 regulatory modernisation

The most significant recent change was the 2022 regulatory modernisation package, which replaced the former RDC 185/2001 framework with a new suite of regulations:

Former regulationReplaced by
RDC 185/2001 (registration)RDC 751/2022
RDC 16/2013 (GMP)RDC 752/2022
RDC 67/2009 (adverse events)RDC 753/2022
RDC 16/2013 (labelling)RDC 754/2022
RDC 25/2008 (AFE)RDC 755/2022

The 2022 package introduced stricter clinical evidence requirements, a more structured PMS framework, and closer alignment with international standards (IMDRF, ISO).

Monitor the What's New section for ongoing regulatory changes.


Official sources

Verify all information against official ANVISA sources before making regulatory decisions.