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IVD Classification

What is an IVD?

An in vitro diagnostic (IVD) medical device is any device — including reagents, kits, instruments, and software — intended to examine specimens derived from the human body, such as blood, urine, tissue, or swabs, to provide information for diagnosis, monitoring, or prognosis.

IVDs notified under Schedule II of MDR 2017 are subject to CDSCO licensing.

IVD risk classification

IVDs follow a distinct classification track based on two axes:

  1. Risk to the individual patient (personal health consequence of incorrect result);
  2. Risk to public health (impact of widespread incorrect results, e.g., for communicable disease screening).
ClassRisk profileExamples
Class ALow individual / low public healthGeneral chemistry reagents, blood cell counters
Class BModerate individual / low public healthPregnancy tests, fertility hormones, PSA kits
Class CHigh individual / moderate public healthBlood glucose meters, blood gas analysers, HbA1c
Class DHigh individual / high public healthHIV, Hepatitis B/C, blood group typing, COVID-19

Regulatory pathway for IVDs

Class A IVDs: Form MD-15 (registration). Class B, C, D IVDs: Form MD-14 (full import licence via CDSCO / SUGAM).

Performance data (analytical and clinical) from CDSCO-notified or internationally accredited laboratories is required for Class C and D IVDs.