Conditional Marketing Authorization
Conditional Marketing Authorization allows MFDS to approve novel or innovative devices based on preliminary evidence, with conditions requiring additional data collection post-approval.
When it appliesβ
Conditional authorization may be granted when:
- The device addresses a serious or life-threatening condition with limited treatment options
- Preliminary evidence is sufficiently promising but a full evidence package is not yet available
- The benefit of early patient access outweighs the risk of residual uncertainty
Conditions typically imposedβ
- Mandatory post-market clinical follow-up (PMCF) study
- Restricted indication or patient population
- Enhanced pharmacovigilance/device surveillance
- Time-limited approval β must be converted to full approval upon data submission
Risk to the manufacturerβ
If the conditions are not fulfilled (e.g., PMCF study not completed), MFDS may revoke the conditional authorization. Planning for compliance is essential from the outset.