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NOM-137-SSA1-2008 — Labelling

NOM-137-SSA1-2008 (Etiquetado de Dispositivos Médicos) is the mandatory labelling standard for medical devices in Mexico. All medical devices marketed in Mexico must carry a Spanish-language label compliant with this NOM.

Publication and status

  • Published: 2008 in the Diario Oficial de la Federación.
  • Status: In force. A significant draft update (PROY-NOM-137-SSA1-2024) was published for public comment and is under finalisation as of early 2026.

Core requirements

NOM-137-SSA1-2008 requires labels to include:

  • Device name (generic and trade name).
  • Manufacturer name and address.
  • Mexico Registration Holder (MRH) name and address.
  • COFEPRIS sanitary registration number (homoclave).
  • Lot or serial number.
  • Expiry date or manufacturing date.
  • Storage and handling conditions.
  • Single-use designation ("Para uso único") where applicable.
  • Sterility statement and method.
  • Warnings and precautions in Spanish.
  • Instructions for use reference (full IFU must accompany the device).

Language requirement

All labelling must be in Spanish. Bilingual labels (Spanish + country-of-origin language) are permissible, provided the Spanish content is complete and accurate.

Draft update — PROY-NOM-137-SSA1-2024

A draft revision was published for public comment in 2024. Expected changes include:

  • Alignment with current international labelling standards (ISO 15223-1:2021 symbols).
  • Updated provisions for electronic or digital IFU (e-IFU) — allowing digital instructions for use under defined conditions.
  • Clarification of requirements for combination products.
  • Updated provisions for IVD labelling consistent with international practice.
Monitor DOF for publication

As of early 2026, NOM-137-SSA1-2024 had not been formally published. Monitor the DOF and What's New for the finalisation date and any transition period.

Access the official text

Available through:

  • DOF (dof.gob.mx) — search "NOM-137-SSA1-2008".
  • COFEPRIS website — labelling guidance section.