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Custom-Made Device Pathway

A custom-made device (dispositivo a medida) is a device manufactured specifically for an individual patient based on a written prescription or order from a qualified health professional (physician, dentist, etc.), tailored to that patient's unique anatomical characteristics or clinical needs.

Exemption from standard registration

Custom-made devices are generally exempt from the standard COFEPRIS sanitary registration requirement, as they are made for a specific patient rather than for general commercial supply.

This exemption applies when:

  • The device is manufactured for a named individual patient.
  • It is based on a written prescription from a qualified health professional.
  • It is not placed on the broader market (i.e., not available for general sale).

Applicable requirements

Despite the registration exemption, custom-made devices must still comply with:

  • GMP principles (NOM-241-SSA1-2025) — the manufacturer must operate a quality system appropriate to the scale and risk of their operations.
  • Labelling — the device must carry a label identifying it as a custom-made device for a specific patient.
  • Traceability — records linking the device to the patient prescription and manufacturing details must be maintained.
  • Technovigilance — adverse events related to custom-made devices should still be reported to CNFV.

What constitutes a custom-made device?

The exemption does not apply to:

  • Devices manufactured using standardised production methods, even if adapted in size or dimension.
  • Devices produced in serial runs for multiple patients (these require standard registration).
  • Devices that are regularly available but chosen for a specific patient — selection is not customisation.

Common examples in Mexico

  • Dental prostheses and orthotics made to individual impressions.
  • Orthopedic braces fabricated to patient measurements.
  • Hearing aids custom-fitted to an individual.
  • Cranial implants made from patient-specific imaging data.