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Registration Fees & Timelines

COFEPRIS charges mandatory government fees (derechos) for sanitary registration applications and renewals. Fees are assessed per product and vary by device class.

New registration fees (one-time)​

Device classFee (MXN)Approx. USD
Class I Low Risk / Annex 1MXN 16,499~USD 930
Class IMXN 16,499~USD 930
Class IIContact COFEPRIS / see current fee schedule—
Class IIIContact COFEPRIS / see current fee schedule—
Fee verification

COFEPRIS fees are set by the annual Ley Federal de Derechos (Federal Rights Law) and may be updated each year. Always verify current fees on the COFEPRIS website or through DIGIPRiS before submitting. The figures above are approximate and may have changed.

Renewal fees​

Device classRenewal fee (MXN)Approx. USD
Class I Low Risk / Class IMXN 12,374~USD 700
Class IIMXN 18,149~USD 1,027
Class IIIMXN 23,098~USD 1,307

Review timelines​

Route & classTarget review period
Equivalency route (all classes)30 working days
Standard route — Annex 1 / Class I20 business days
Standard route — Class I20–30 business days
Standard route — Class II30–60 business days
Standard route — Class III60–180 business days

Actual timelines depend on COFEPRIS workload and the completeness of the submitted dossier. Deficiency letters (prevenciones) pause the clock — applicants must respond within the specified period.

Payment process​

Fees are paid through the DIGIPRiS portal at the time of submission. Proof of payment (pago de derechos) must be included as part of the application package.