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Prefectural vs MHLW Licensing Authority

JP-unique

Licensing authority for MAHs and manufacturers in Japan is split between MHLW (national level) and prefectural governments (local level). Which authority issues a given licence depends on the device class and the nature of the activity. This split is unique to Japan's administrative structure.

Which authority issues which licences

Licence typeIssuing authority
General MAH licence (Class I, II, most Class III devices)Prefectural government where MAH office is located
MAH licence for Class IV / specially designated Class III devicesMHLW
Domestic manufacturing licence — generalPrefectural government where facility is located
Domestic manufacturing licence — specially designated Class III/IVMHLW
Class I Todokede notificationPrefectural government where MAH office is located

Practical implications

For most medical device companies in Japan:

  • The prefectural government of Tokyo is the issuing and oversight authority, since most MAHs and device companies are headquartered in Tokyo
  • Interactions with MHLW directly (rather than through the Tokyo Metropolitan Government) occur for higher-risk device licences and for formal approvals/certifications

Understanding which authority to contact for a specific licence, change, or notification requires knowing both the device class and the MAH's office location.

Tokyo Metropolitan Government Health and Welfare Bureau

The Tokyo Metropolitan Government Health and Welfare Bureau (東京都福祉保健局 — now reorganised under Tokyo Metropolitan Government restructuring) is the most frequently encountered prefectural licensing authority in the medical device industry, given Tokyo's concentration of MAHs and device manufacturers. Their processes and timelines are broadly similar to other prefectures but may have Tokyo-specific administrative practices.