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Post-market overview & ongoing responsibilities

Regulatory basis

Post-market obligations under the UK MDR 2002 derive from multiple provisions of the Regulations, including Schedule 1 (Essential Requirements for PMS and clinical follow-up), Schedule 3 (conformity assessment surveillance obligations), and the specific vigilance reporting requirements. MHRA enforces post-market obligations actively through market surveillance and inspection.

Disclaimer

This site provides general information only and does not constitute legal or regulatory advice. Always consult the official legislation and MHRA guidance before making regulatory decisions.


Post-market compliance is not optional

Placing a device on the GB market is not the end of the manufacturer's regulatory obligations — it is the beginning of a new phase. Post-market compliance under UK MDR 2002 is a continuous, lifecycle-long obligation.

Manufacturers, UKRPs, importers, and distributors all have ongoing responsibilities once a device is on the market. Failure to meet post-market obligations can result in:

  • MHRA enforcement action
  • Mandatory recall
  • Suspension or cancellation of UKAB certificates
  • Criminal prosecution
  • Reputational damage and civil liability

The post-market obligation landscape

Post-market obligations cluster into six areas:

AreaWho is primarily responsibleKey obligation
Post-market surveillance (PMS)ManufacturerProactive monitoring of real-world device performance
Vigilance reportingManufacturer / UKRPReporting serious incidents and trend data to MHRA
Field Safety Corrective Actions (FSCAs)Manufacturer / UKRPTaking corrective action in the field when safety issues arise
MHRA registration maintenanceManufacturer / UKRPKeeping registration current as devices and company details change
Labelling and advertising complianceManufacturer / distributorEnsuring ongoing compliance with labelling and promotional rules
UKAB surveillanceManufacturerParticipating in annual UKAB surveillance audits; maintaining certification

Who bears post-market responsibilities

Manufacturers

Manufacturers bear the primary post-market obligations — PMS, vigilance reporting, FSCAs, technical file maintenance, and UKAB surveillance cooperation.

UK Responsible Persons (UKRPs)

UKRPs share post-market responsibilities with manufacturers for the GB market:

  • Must transmit serious incident and FSCA reports to MHRA (on behalf of or alongside the manufacturer)
  • Must maintain records and cooperate with MHRA investigations
  • Must notify the manufacturer of any complaints or field reports received in GB

Importers

Importers must:

  • Report devices presenting a serious risk to MHRA and to the manufacturer/UKRP
  • Maintain records of imports (minimum 5 years, 15 years for implantables)
  • Not continue to supply a device they know to be non-compliant

Distributors

Distributors must:

  • Report devices suspected of presenting a serious risk to MHRA and to the manufacturer/UKRP
  • Cooperate with any recall or FSCA
  • Maintain traceability records

The feedback loop: post-market to pre-market

Post-market data does not exist in isolation — it must feed back into the pre-market evidence base:

Post-market surveillance data
Adverse event reports
PMCF study results
PSUR conclusions


Risk management file update
(new hazards? changed risk estimates?)


Clinical Evaluation Report update
(new clinical evidence? changed benefit-risk?)


Technical file update
(revised ERs checklist, new test data if needed)


UKAB notification if significant design change

A manufacturer who treats post-market surveillance as a compliance formality — rather than a genuine source of safety intelligence — is failing both their patients and their regulatory obligations.


MHRA's post-market enforcement tools

MHRA has a range of tools to enforce post-market compliance:

ToolDescription
Market surveillanceMHRA can inspect devices on the market, request technical files and DoCs, and test devices
Manufacturer inspectionMHRA can inspect manufacturing premises and QMS records
Vigilance follow-upMHRA investigates serious incident reports and may require corrective action
Recall powersMHRA can mandate recall of devices presenting a serious risk
Enforcement noticesMHRA can issue notices requiring a manufacturer to take specific action
Prohibition noticesMHRA can prohibit the supply of a non-compliant device
Criminal prosecutionMHRA can prosecute for serious violations of the UK MDR 2002
UKAB certificate suspensionMHRA can instruct a UKAB to suspend or withdraw a certificate


Official references

ReferenceDescription
UK MDR 2002 (SI 2002/618 as amended)Post-market obligations throughout the Regulations
MHRA: Post-market surveillance guidanceMHRA's PMS guidance
MHRA: Adverse incident reportingVigilance reporting requirements
ISO 13485:2016, Clause 8Measurement, analysis, and improvement — post-market QMS
ISO 14971:2019Risk management — post-market risk monitoring