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Systems & procedure packs

Regulatory basis

Systems and procedure packs are addressed in Regulation 12 of the UK MDR 2002. The person assembling a system or procedure pack has defined obligations under UK MDR 2002, which differ from those of a manufacturer.


What is a system or procedure pack?

A system is a combination of products packaged together and intended to be interconnected or combined to achieve a specific medical purpose.

A procedure pack is a combination of products packaged together to be used for a specific medical intervention or procedure.

Examples:

  • A sterile surgical pack containing drapes, gowns, and instruments for a specific operation
  • A wound care pack combining a dressing, saline, and applicators
  • A catheterisation pack combining a catheter, drainage bag, and lubricant
  • A vascular access pack combining a catheter, needle, and fixation dressing

Who assembles systems and procedure packs?

Systems and procedure packs are typically assembled by:

  • Medical device distributors or wholesalers
  • Hospital central sterile supply departments (CSSDs)
  • Contract pack assemblers

The assembler may or may not be the manufacturer of any of the individual components.


The assembler's obligations

Under Regulation 12, the assembler of a system or procedure pack must ensure that:

  1. All individual components in the pack bear the UKCA mark (or CE mark under transitional acceptance) — i.e., they are individually compliant medical devices (or other compliant products)
  2. The combination and packaging does not compromise the safety and performance of the individual components
  3. The system or procedure pack bears the assembler's name, address, and trade name (if any)
  4. Where the pack is supplied sterile: the sterilisation is validated and the pack bears the required sterility labelling

The assembler must prepare a statement (equivalent to an Annex XII statement in EU MDD terms) that:

  • Identifies the components in the pack and confirms they bear the UKCA/CE mark
  • Confirms that the combination process was carried out in accordance with the manufacturers' instructions
  • Confirms that the assembly did not compromise individual device compliance

When does assembling a pack make you a manufacturer?

If the assembler combines devices in a way not envisaged by any individual manufacturer — creating a new combination that constitutes a new device with its own claims and indications — the assembler may become the manufacturer of a new medical device.

This is a key distinction:

ScenarioRegulatory position
Assembling individually compliant devices into a pack per their manufacturers' instructionsAssembler under Regulation 12 — simplified obligations
Creating a new combination with new claims, new intended purpose, or sterilising without a validated processManufacturer of a new medical device — full UK MDR 2002 obligations


Official references

ReferenceDescription
UK MDR 2002, Regulation 12Systems and procedure packs
MHRA: Systems and procedure packs guidanceMHRA guidance
EU MDD 93/42/EEC, Article 12Source provision for UK Regulation 12